What Does an HBsAg Rapid Test Detect?

The Hepatitis B surface antigen (HBsAg) rapid test is a diagnostic tool used to detect the presence of the Hepatitis B virus (HBV) in the blood. HBsAg is a protein on the surface of the Hepatitis B virus; the presence of HBsAg indicates that a person is infected with HBV and can transmit the virus to others. This test is crucial as it allows for the timely diagnosis and management of HBV, which can prevent the progression to severe liver disease such as cirrhosis or hepatocellular carcinoma.

The rapid test is an immunoassay based on the principle of binding of antibodies to antigens. The test involves a small blood sample and provides results in approximately 15-30 minutes, making it practical for use in various healthcare settings, from clinics to community health programs.

HBsAg Rapid Test: Technical Parameters

The performance of the HBsAg rapid test is evaluated using several parameters:

• Sensitivity: Typically above 95%, indicating the test's ability to correctly identify those with the infection.
• Specificity: Usually above 98%, meaning the test's ability to correctly identify those without the infection.
• Limit of Detection (LOD): Often around 0.1 ng/mL, which is the minimum concentration of HBsAg that can be reliably detected.

QL Biotech Company Solutions

QL Biotech is a leading biotechnology company that offers advanced solutions for HBsAg detection. Their product portfolio includes the following:

1. QL Rapid HBsAg Test Kit

This kit provides rapid detection of Hepatitis B surface antigen using a lateral flow immunoassay technique. It is designed for easy use and provides quick results without the need for specialized equipment.

• Sensitivity: Greater than 99%.
• Specificity: Greater than 99%.
• Time to Result: 15 minutes.

2. QL Automated HBsAg Analyzer

This is a high-throughput solution suitable for laboratories. It automates the testing process, allowing simultaneous testing of multiple samples.

• Throughput: Up to 120 tests per hour.
• Analytical Sensitivity: 0.05 ng/mL.
• Automation Level: Full sample-to-result integration.

References

1. World Health Organization. Hepatitis B Fact Sheets. WHO, 2023.
2. Centers for Disease Control and Prevention. Understanding Hepatitis B. CDC, 2023.
3. QL Biotech. HBsAg Rapid Detection Technologies. QL Biotech, 2023.
4. Togashi, T. et al. Advancements in Rapid Hepatitis B Testing. Journal of Clinical Virology, vol. 150, 2022, pp. 45-53.