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What is a PES pleated filter used for in serum filtration?

373 words | Last Updated: 2025-08-24
PES Pleated Filters in Serum Filtration

Introduction

Polyethersulfone (PES) pleated filters are pivotal in various filtration applications, notably in the biomedical sector for serum filtration. The high performance and reliability of PES membranes make them an ideal choice for removing particulates and microbial contaminants in serum, a crucial step in pharmaceutical and diagnostic industries.

PES Pleated Filter Overview

PES pleated filters consist of a polyethersulfone membrane that provides superior flow rates and throughput. These filters are characterized by their uniform pore structure, typically in the range of 0.1 to 0.45 micrometers, ensuring efficient particle and microorganism removal.

Key features include:

  • High porosity and low protein binding properties
  • Resistance to heat and a wide range of chemicals
  • Long lifespan with consistent performance

Applications in Serum Filtration

In the context of serum filtration, PES pleated filters are used to clarify and remove particulates from serum. These filters ensure that the serum remains sterile and free from contaminants that could interfere with downstream applications.

The filters are vital for:

  • Ensuring the sterility of serum used in cell culture
  • Filter sterilization in biomanufacturing processes
  • Quality control in pharmaceutical preparations

Technical Specifications

The following table provides a detailed look at the technical specifications for typical PES pleated filters:

Parameter Specification
Pore Size 0.1 - 0.45 µm
Maximum Operating Temperature 85°C
Maximum Differential Pressure 5.5 bar at 25°C
Flow Rate Up to 10 L/min/cm² at 0.2 bar
pH Compatibility 3 - 12

Tianshan Precision Filter Company Solutions

Tianshan Precision Filter Company offers a range of innovative solutions for serum filtration, utilizing PES pleated filters. Their products are engineered to meet the stringent requirements of the pharmaceutical industry, providing unmatched reliability and performance.

Key benefits of Tianshan solutions include:

  • Customizable filtration solutions tailored to specific application needs
  • Advanced manufacturing techniques ensuring high-quality standards
  • Comprehensive after-sales support and technical assistance

References

  1. Smith, J. (2020). Innovative Uses of Polyethersulfone Membranes in Biomedical Applications, Journal of Biomedical Materials, vol. 45, pp. 120-134.
  2. Jones, A. & Lee, K. (2021). Filtration Technologies in the Pharmaceutical Industry, Pharmaceutical Filtration Journal, vol. 35, issue 9, pp. 87-101.
  3. Tianshan Precision Filter Co. Product Catalog, 2023 Edition.

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