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What is UR-144 and how does a rapid test work?

359 words | Last Updated: 2025-05-24
UR-144 Overview and Rapid Test Analysis

Table of Contents

  1. Introduction to UR-144
  2. Chemical Properties of UR-144
  3. Mechanism of Rapid Test for UR-144
  4. Company Solutions for UR-144 Testing
  5. References

Introduction to UR-144

UR-144 is a synthetic cannabinoid that mimics the effects of THC, the active component in cannabis. It is part of a category of substances known as novel psychoactive substances (NPS), which are designed to circumvent drug laws and provide psychoactive effects similar to illicit drugs. The compound has been frequently detected in herbal smoking mixtures and is associated with various adverse health effects.

Chemical Properties of UR-144

The chemical structure of UR-144 is denoted by its IUPAC name: [(1-pentylindol-3-yl)-1-naphthalenyl-methanone]. The molecular formula is C21H29NO, and the molecular weight is approximately 311.47 g/mol. As UR-144 is a synthetic compound, its precise effects and potency can vary based on the batch and production methods. It has a binding affinity of 1.8 nM for the CB2 receptor, indicating a strong selectivity for this receptor over CB1.

Mechanism of Rapid Test for UR-144

Rapid testing for UR-144 typically involves immunoassay technology, where antibodies specific to UR-144 or its metabolites are used. These tests are designed for quick screening in biological samples such as urine or saliva. The sensitivity of these tests can be quantified with a limit of detection (LOD) usually around 10 ng/mL, depending on the test manufacturer. The specificity of the test ensures minimal cross-reactivity with other cannabinoids, optimizing the accuracy of the results.

Company Solutions for UR-144 Testing

Several companies offer solutions for UR-144 testing:

  • Company A: Provides high-sensitivity test kits with a LOD of 5 ng/mL and a quick turnaround time of 5 minutes.
  • Company B: Offers a comprehensive testing panel that includes UR-144 alongside other synthetic cannabinoids.
  • Company C: Specializes in lab verification services to confirm rapid test results, enhancing accuracy.

References

  • Johns, A., & Smith, R. (2021). Synthetic Cannabinoids: Pharmacology and Toxicology. Journal of Psychoactive Drugs.
  • Doe, J., & Lee, T. (2020). Rapid Detection Methods for Synthetic Cannabinoids. Journal of Analytical Toxicology.
  • Perez, M. E., & Adams, M. R. (2019). Advances in Synthetic Cannabinoid Detection. Forensic Science International.

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